Ruminococcus gnavus bacteremia associated with fecal peritonitis secondary to small bowel perforation
Journal | Volume 81 - 2018 |
Issue | Fasc.3 - Letters |
Author(s) | M. Struyve, C. De Vloo, S. Lefever, M. Boudewijns, A. De Bel, M. D'Hondt, M. del Carmen Alegret Pampols, W. Van Moerkercke, D. Van den Bossche |
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(1) Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium ; (2) Department of Gastroenterology, Ziekenhuis Oost-Limburg (ZOL), Genk, Belgium ; (3) Department of Laboratory Medicine, University Hospital Gasthuisberg, Leuven, Belgium ; (4) Department of Microbiology, AZ Groeninge, Kortrijk, Belgium ; (5) Department of Abdominal Surgery, AZ Groeninge, Kortrijk, Belgium ; (6) Department of Anaesthesiology and Intensive Care, AZ Groeningen, Kortrijk, Belgium ; (7) Department of Gastroenterology, AZ Groeninge, Kortrijk, Belgium |
Ruminococcus gnavus is a common and abundant member of the human gut microbiota. Infections due to R. gnavus have been reported only rarely. In this letter, we illustrate the importance of a comprehensive and up-to-date database for rapid and accurate identification of anaerobic bacteria by matrix-assisted laser desorption ionization-time of flight mass spectrometry. We report a case of bacteremia with R. gnavus associated with fecal peritonitis secondary to a small bowel strangulated hernia and perforation (Fig. 1a,b). Surgical resection of a gangrenous small bowel segment and abdominal lavage was performed. Anaerobic blood cultures on day +5 revealed catalase negative Gram-positive diplococcic. Species identification was performed using partial 16S rRNA gene sequencing (MicroSeq 500 kit, Life Technologies, Foster City, CA) and MALDI BioTyper (software version 3.1; library version 4.0.0.1) MALDI-TOF MS system (Bruker Daltonics, Germany). Species identification of the isolate as R. gnavus was confirmed. Patient was treated with antibiotics and discharged 12 weeks after admittance. |
© Acta Gastro-Enterologica Belgica. PMID 30350543 |